Jurnal Veteriner Nusantara

Studi In Silico: Potensi Senyawa Spesifik Kulit Batang Faloak (Sterculia quadrifida R. Br) sebagai Anti-Helmintik

2025-10-11T23:05:42+00:00

Helminthiasis remains a significant global public health issue, particularly in tropical and subtropical regions. The extensive and repeated use of synthetic anthelmintic agents, including albendazole and mebendazole, has contributed to the emergence of drug resistance among various parasitic species. Therefore, the exploration of plant-derived compounds with potential anthelmintic activity is urgently needed. This study investigated the potential of bioactive compounds from the stem bark of Faloak (Sterculia quadrifida R. Br) as inhibitors of the Mitochondrial Rhodoquinol-Fumarate Reductase (MRFR) protein through an in silico approach. Five compounds: epicatechin, d-catechin, catechin-(4α→8)-catechin, spinasterol, and spinasterone were analyzed, with Atpeni as the control. Drug-likeness evaluation was conducted using Lipinski’s Rule of Five, while molecular docking, visualization and molecular interaction analysis was performed using PyRx, PyMOL, and Discovery Studio. Four compounds satisfied Lipinski’s criteria, indicating favorable pharmacokinetic properties. Among them, spinasterol and spinasterone demonstrated the strongest binding affinities to MRFR (–10.1 and –9.2 kcal/mol, respectively), exceeding that of the control ligand (–6.4 kcal/mol). Hydrophobic interactions involving key residues such as Leu146, Ala149, and Val153 contributed to complex stability. These results suggest that Faloak stem bark contains promising bioactive compounds that may serve as natural anti-helmintic candidates, warranting further in vitro and in vivo validation

Pengaruh penambahan sari daun binahong kedalam pengencer Tris kuning telur terhadap kualitas semen cair Babi persilangan landrace dan duroc

2025-10-16T06:20:51+00:00

Tujuan penelitian ini adalah untuk mengetahui pengaruh penambahan ekstrak daun binahong (SDB) dalam pengencer telur tris yolting (T-kt) terhadap kualitas spermatozoa babi hasil persilangan landrace x duroc. Bahan yang digunakan dalam penelitian ini adalah semen segar dari babi hasil persilangan landrace x duroc umur 1,5 tahun dalam kondisi sehat dan telah dibor untuk koleksi semen. Penelitian ini menerapkan metode eksperimen dengan perencanaan acak lengkap (RAL) yang melibatkan 6 perlakuan dan 5 ulangan, yaitu: P0 = T-KT + SDB, 0%, P1 = T-KT + SDB, 0,5% P2 = T-KT + SDB, 1% P3 = T-KT + SDB, 1,5% P4 = T-KT + SDB, 2%, P5 = T-KT + SDB, 2,5%. Variabel yang diteliti adalah motilitas, viabilitas, abnormalitas, dan viabilitas spermatozoa. Semen yang telah encer disimpan dalam pendingin pada suhu 15-20℃ dan dievaluasi setiap 12 jam. Berdasarkan hasil penelitian, dapat disimpulkan bahwa perlakuan P2 dengan konsentrasi 1% (SDB) menunjukkan motilitas 57,00±2,74%, viabilitas 66,70±3,90%, abnormalitas 5,00±0,61%, dan rentang hidup 56,20±1,54 jam.

Pengaruh Tinggi Pemotongan Terhadap Kecernaan In Vitro Bahan Kering dan Bahan Organik serta Total Digestible Nutrient (TDN) Rumput Gajah Mini (Pennisetum purpureum cv. Mott) Panen Kedua

2025-10-16T06:44:54+00:00

The aim of this study was to determine the effect of cutting height on the in vitro digestibility of dry matter and organic matter, as well as total digestible nutrients (TDN), in elephant grass (Pennisetum purpureum cv. Mott). A completely randomized design (CRD) was used with five treatments and three replications. T1 was a cutting height of 5 cm above ground level, T2 was a cutting height of 10 cm above ground level, T3 was a cutting height of 15 cm above ground level, T4 was a cutting height of 20 cm above ground level, and T5 was a cutting height of 25 cm above ground level. The in vitro digestibility of dry matter and organic matter, as well as total digestible nutrients (TDN), was investigated. Data were analyzed using analysis of variance (ANOVA). The results of the analysis of variance showed that the in vitro digestibility of dry matter, organic matter, and total digestible nutrients (TDN) of Pennisetum purpureum cv. Mott was not affected by cutting height (P>0.05). The results showed that cutting height had a similar effect on dry matter, organic matter, and TDN. At a cutting height of 5 cm above the ground, the average in vitro digestibility of dry matter, organic matter, and TDN was 72.429%, 71.865%, and 62.658%, respectively.

Knowledge, Attitudes, and Practices (KAP) of Communities toward Rabies Prevention in Indonesia: A Literature Review

2025-10-12T17:38:35+00:00

Rabies remains a serious zoonotic threat in Indonesia, with thousands of animal bite cases and dozens of human deaths annually. This review article aims to identify the level of community knowledge, attitudes, and practices (KAP) regarding rabies prevention in Indonesia and highlight the importance of a socio-cultural approach in supporting the national rabies elimination program. Data have been collected from scientific articles published between 2015 and 2025. Results indicate that the community’s basic knowledge about rabies is quite high, but there is still a gap between knowledge and actual practice, especially in rural and eastern Indonesia. The involvement of traditional leaders and a One Health approach is recommended to improve the effectiveness of education and compliance with rabies prevention.

Pneumonia Karena Migrasi Larva Toxocara sp.dan Ancylostoma sp. pada Kucing Domestik

2025-08-18T23:57:52+00:00

A 2-year-old domestic cat named Simba presented with respiratory symptoms, including coughing and nasal discharge containing serous exudate. Additionally, the cat exhibited abdominal enlargement. During the physical examination, palpation of the trachea triggered a coughing reflex, and the cat appeared to be attempting to expel something from its throat. Fecal examination revealed the presence of Toxocara sp. and Ancylostoma sp. eggs. A routine hematology test showed leukocytosis, lymphocytosis, monocytosis, granulocytopenia. The cat was diagnosed with pneumonia caused by the migration of Toxocara sp. and Ancylostoma sp. larvae.Treatment was given with Pyrantel pamoate (Combantrin®) 125 mg/tab with a dose of 40 mg (1/3 tab) orally once a week for two weeks, repeating depending on the severity, Amoxyclav antibiotic 625 mg/tab with a dose of 64 mg (1/10) orally twice a day for 7 days, and fish oil (Tung-hai Fish Liver Oil®) orally one soft gel per day for 7 days. An evaluation on the seventh day showed that the cat’s condition had improved.

Studi Kasus : Kejadian Penyakit Pada Farm Ayam Broiler Di Wilayah Kabupaten Cianjur

2025-08-19T00:00:34+00:00

Therefore, early identification and analysis of disease causes are
essential, particularly through preliminary examinations such as
antibody titer measurement and anatomical pathology observation. In
addition, laboratory testing for parasites, viruses, and bacteria plays
a crucial role in establishing an accurate diagnosis and supporting
effective treatment decisions. The case animal in this report is a white
broiler chicken exhibiting clinical signs of illness. The chicken was
sourced from a poultry farm located in Cianjur Regency and had
shown symptoms of disease for four consecutive days. Clinical signs
observed included lethargy, reduced appetite, weight loss, dull
plumage, swelling, and occasional abnormal respiratory sounds
(gurgling or "ngorok"). The diagnostic approach included serological
testing to assess the immune response and anatomical pathology
examination. Based on the clinical presentation, a differential
diagnosis of Newcastle Disease was considered.

Studi Kasus : Identifikasi Toxocara cati pada Kucing di Rumah Sakit Hewan Universitas Hasanuddin

2025-08-29T03:03:36+00:00

Toxocariasis is a zoonotic disease caused by infection with the parasitic worm Toxocara cati, which commonly infects cats and can be transmitted to humans. This study aimed to identify the presence of T. cati in cats through macroscopic and microscopic examination of fecal samples. Samples were collected from post-operative cats exhibiting clinical signs such as lethargy and decreased appetite, with adult worms observed in their feces. Examination was conducted using the flotation method with a saturated salt solution. The results revealed the presence of adult T. cati worms with distinct morphological features, including cervical alae on the anterior end and a curved posterior end. Additionally, round-shaped eggs with thick, rough brownish walls were identified. These findings highlight the importance of routine parasitological examinations and regular deworming to prevent the spread of toxocariasis. Maintaining environmental hygiene and feed quality also plays a crucial role in controlling this disease.

Studi Kasus: Penanganan Prolapsus Ani dengan Enterektomi pada Kucing Domestik di Rumah Sakit Hewan Jawa Barat

2025-09-10T05:48:45+00:00

Domestic cats are one of the types of animals commonly kept as pets
in Indonesia. Stray cats are a type of domestic cat that can also be
kept as pets because they are capable of socializing with humans.
However, due to their behavioral patterns and the lack of proper pet
management, stray cats are often exposed to diseases and can become
carriers for other cats. On September 9, 2024, a male cat named Kucil,
approximately 4 months old and weighing around 2 kg, was brought
to the West Java Provincial Animal Hospital with a complaint of a
mass protruding from the anus. The purpose of this case study is to
determine the diagnosis and management of prolapsed rectum in
domestic cats. The diagnostic methods used included anamnesis,
physical examination, and supporting tests, such as blood hematology.
The physical examination revealed a body temperature of 38.5°C and
a capillary refill time (CRT) of less than 2 seconds. Upon performing
an inspection of the anus, a mass was found protruding through the
anus, leading to the diagnosis of prolapsed rectum in Kucil. The
treatment involved an enterectomy or surgical removal of the intestine
that had prolapsed from the anus. Post-operative therapy included
antibiotics, anti-inflammatory drugs, and vitamins