GAMBARAN HISTOPATOLOGI BEBERAPA TIPE BRONCHOPNEUMONIA PADA PULMO BABI HASIL PEMOTONGAN DI RPH OEBA
Abstract
The aim of this study was to determine the histopathologic changes of bronchopneumonia type in pigs of slaughtered pig from Oeba slaughterhouse associated with P. multocida infection. Samples of pulmo were found from pigs showing respiratoric symptoms, characterized as dyspnoea and presence of nasal exudates that are serous to mucopurulent, obtained from slaughtered pigs in RPH Oeba Kota Kupang. Samples showed pathognomonic lesions of gray hepatized than processed for histopathological studies. The result showed that varied macroscopic changes noted in pulmo samples from suspected infected pigs showed various types of lesions. Lessions observed then classified into two main lessions were acute and chronic. Acute lesions were characterized by edema and hyperemia which then confirmed with congestion and multifocal haemorrhages. Serous to seromucous exudates were observed intrabronchial and bronchioles. In chronic cases, the lesions showed cranioventral consolidation and gray hepatized with demarcated area beetwen consolidated and normal pulmonary area. Histologically, the types of bronchopneumonia categorized into bronchopneumonia suppurativa characterized by coagulative necrosis surrounded by cell infiltration and accumulation of fibrin intraalveolar. The fibrous connective tissue were also observed in the interstitaial space of alveolar around the necrotic area. Other samples showed non-suppurativa fibrinous bronchopneumonia with alveolar exudates dominated by mononuclear cells and accumulation of fibrin intra alveolar. Chronic bronchiolitis also seen with a mixture of mononuclear cells, neutrophils and macrophages that infiltrated into the lumen of the alveoli. A high number of goblet cells were observed in the bronchiolus epithelium, with the thickening of the fibrous tissue around the bronchioles. It can be concluded that there are two major types of lesions which are acute and chronic, with three types of bronchopnemonia namely bronchopneumonia suppurativa, non supuratival bronchopneumonia and chronic bronchiolitis.
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Backstrom, L. R., Brim, T. A., and Collins, M. T. 1988. Development of turbinate lesions and nasal colonization of Bordetella bronchi septica and Pasteurella multocida during long term exposure of healthy pigs affected by atrophic rhinitis. Can. J. Vet. Res. 52:23–29.
Biro Pusat Statistik Nusa Tenggara Timur, 2016. Populasi ternak kecil menurut jenis ternak menurut kabupaten/kota, 2013. Available on [http://www.BPS NTT/PDF/Techinical%20no.41.pdf]. [diunduh 28 Maret 2016].
Cameron, R. D. A., 2000. A Review of the industrialization of pig production worldwide with particular reference to the asian region. Animal health and Area-wide Integration. Brisbane, Australia. Pp.22-37.
Cameron, R.D., O’Boyle, D., Frost A.J., Gordon A.N., and Fegan, N., 1996. An outbreak of haemorrhagic septicaemia associated with Pasteurella multocida subsp gallicida in large pig herd. Aust. Vet. J.,73:27–29.
Carter, G.R. dan Wise, D.J., 2004. Essentials of Veterinary Bacteriology and Mycology. 6th Ed. Iowa State Press. Ames, Iowa, Pp. 149-151.
Carter, G. R. & de Alwis, M. C. L. 1989. Haemorrhagic septicaemia. In Pasteurella and Pasteurellosis. C. F. Adlam & J. M. Rutter. (Ed.) Academic Press London. Pp. 131–160.
Caswell, J.L. and Williams, K.J., 2007. Respiratory system. In: Jubb, Kennedy, and Palmer's Pathology of Domestic Animals, Elseviers Saunders, Chicago. Pp. 589-593; 1406.
Davies, R. L., MacCorquodale, R., Baillie, S. and Caffrey B., 2003. Characterization and comparison of Pasteurella multocida strains associated with porcine pneumonia and atrophic rhinitis. J. Med. Microbiol. 52:59–67.
Gamage, L.N.A., Wijewardana, T.G., Bastiansz, H.L.G., Vipulasiri, A.A., 1995. An outbreak of acute pasteurellosis in swine caused by
serotype B:2 in Sri Lanka. S.L. Vet. J., 42:15-19.
Hansen, M.S., Pors, S.E., Jensen, H.E., V.B. Hansen, Bisgaard, M., Flachs, E.M. and Nielsen, O.L., 2010., An investigation of the pathology and pathogens associated with porcine respiratory disease complex in Denmark. J. Comp. Pathol., 143:120–131.
Harish, B.R., Chandranaik, B.M., Venkatesh, M.D., Renukaprasad, C., Jayakumar, S.R. and Krishnapp, G. (2005) An outbreak of swine Pasteurellosis and its pathology. Indian J. Vet. Pathol.,29(2): 129-130.
Jamaludin, R., Blackall, P.J., Hansen, M.F., Humphrey, S., Styles, M., 2005. Phenotypic and genotypic characterisation of Pasteurella multocida isolated from pigs at slaughter in New Zealand. N. Z. Vet. J. 53:203-20.
Kyrizakis, I., and Whittemore, C. T., 2006. Whittemore’s Science and practice of pig production, 3rd Ed., Blackwell Publishing, Victoria, Pp.291-303.
Kumar, H., Mahajan, V., Sharma, S., Alka, Singh R., Arora, A. K., Banga, H. S., Verma, S., Kaur, K., Kaur, P., Meenakshi, Sandhu, K. S., 2007. Concurrent pasteurellosis and classical swine fever in Indian pigs. Journal of Swine Health and Production. 15(5):279-283.
Lopez, A. 2001. Respiratory System, Thoracic Cavity and Pleura. In: Thomson’s Special Veterinary Pathology, 3rd Ed. McGavin, M. D., Carlton W. W. & Zachary, J., (Eds.), Mosby-Year Book Inc., Pp. 125-195.
Pijoan, C., Morrison, R. B., and Hilley, H. D.. 1983. Serotyping of Pasteurella multocida isolated from swine lungs collected at slaughter. J. Clin. Microbiol. 17:1074–1076.
Pijoan, C., 2006. Pneumonic pasteurellosis. In: Diseases of Swine, 9th ed. (Eds.) Straw B. et al. Ames, IA: Iowa State University Press. Blackwell Publishing Australia. Pp. 719-725.
Pors, S. E., Hansen M. S. , Bisgaard, M., , Jensen, H. E. , 2011. Occurrence and associated lesions of Pasteurella multocida in porcine bronchopneumonia. Vet. Microbiol. 150 (1-2):160-166.
Radostits, M., Gay, C.C., Hinchcliff K. W., P. D. Constable. 2006. Veterinary Medicine: A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs and Goats. 10th ed. Saunders-Elsevier. London. Pp. 950-952.
Radostits, O. M., Gay, C. C., Blood, D. C., and Hinchcliff, K. W. 2000. Veterinary Medicine: A Textbook of Diseases of Cattle, Sheep, Pigs, Goats and Horses. 9th ed., W.B. Saunders. Pp. 921-945.
Straw, B.E, Zimmerman, J.J, D’allaire S., Taylor, D.J., 2006. Disease of Swine. Blackwell publishing. Iowa, Pp.577-602.
Thacker, E.L. 2006. Mycoplasmal Disease, Diseases of Swine. 9th ed. Iowa State University Press, Ames. Pp 701-717.
Townsend, K.M., O'Boyle, D., Phan, T.T., Hanh, T.X., Wijewardana,
T.G., Wilkie, I., Trung, N.T., Frost, A.J., 1998. Acute septicaemic pasteurellosis in Vietnamese pigs. Vet. Microbiol. 63:205-215.