LITERATUR REVIEW COMPARISON OF THE EFFECTIVENESS OF (Moringa oleifera) EXTRACT WITH KETOCONAZOL IN INHIBITING THE GROWTH OF Candida sp. ON Saboraud Dextrose Agar
-
Lidya Lyke Sonbait(1)
Universitas Nusa Cendana
-
Prisca Deviani Pakan(2)
Universitas Nusa Cendana
-
Idawati Trisno(3)
Universitas Nusa Cendana
-
Christina Olly Lada(4*)
Universitas Nusa Cendana
(*) Corresponding Author
Abstract
Background: One of the fungi that often causes infectious diseases is Candida albicans with a worldwide prevalence of 66%. Candidiasis as a disease caused by Candida albicans infection can be found throughout the world and is able to attack all ages, both men and women.
Purpose: To compare the effectiveness of Moringa oleifera plant extract with ketoconazole in inhibiting Candida sp. on Saboraud Dextrose Agar.
Methods: The method of searching for article data sources is carried out through the Google Scholar and PubMed databases (2015-2020) to retrieve relevant articles published in English and Indonesian. Key terms and phrases related to the comparative effectiveness of Moringa oleifera, ketoconazole, Candida sp. growth, Saboraud Dextrose Agar used in the subject search.
Results: Based on the results of a literature review from 23 journals consisting of comparative characteristics of the effectiveness of Moringa oleifera and ketoconazole plant extracts, 11 journals found that ketoconazole Moringa oleifera plant extract was more effective than ketoconazole, while 12 other journals said that ketoconazole was more effective. By doing a comparison between the two methods, it was found that ketoconazole was more effective to be used in inhibiting the growth of Candida sp. than Moringa oleifera plant extract.
Conclusion: Based on 23 journals conducted by a literature review, it can be concluded that ketoconazole has better effectiveness in inhibiting the growth of Candida sp. than Moringa oleifera plant extract.
Downloads
References
2. Puspitasari A, Kawilarang AP, Ervianti E, Rohiman A. Profil Pasien Baru Kandidiasis. Berkala ilmu kesehatan kulit dan kelamin. 2019;31(1)
3. Lestari PE. Peran Faktor Virulensi Pada Patogenesis Infeksi Candida albicans. Stomatognatic (J.K.G Unej). 2010;7(2):113-17
4. Permatasari AAAP, Sari NKY. Efektivitas Antijamur Ekstrak Etanol Bunga Kamboja Putih (Plumeria acuminata) Terhadap Pertumbuhan Candida albicans.2019;2(1)
5.Johan R, Tinea Imbrikata. CDK-245. 2016;43(10)
6. Candrasari A, Romas MA, Hasbi M, Astuti OR. Uji Daya Antimikroba Ekstrak Etanol Daun Sirih Merah (piper crocatum ruiz & pav.) Terhadap Pertumbuhan Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 11229 Dan Candida albicans ATCC 10231 secara in Vitro. Biomedika. 2012;4(1)
7.Siddik MB, Yulia L, Edyson. Perbandingan Efektivitas Antifungi Antara Ekstrak Metanol Kulit Batang Kasturi Dengan Ketokonazol 2% Terhadap Candida albicans in Vitro. Berkala Kedokteran. 2016;12(2):271-278
8.Dewanti LP, Widodo A, Fadhilah E. Pengaruh Pemberian Tepung Daun Kelor (Moringa oleifera) Varietas Nusa Tenggara Timur Terhadap Kadar Albumin Darah Tikus Putih (Rattus norvegicus Strain Wistar) Yang Diberi Diet Non Protein. 2016;1(1)
Copyright (c) 2026 Cendana Medical Journal
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright Notice
This work is licensed under a Creative Commons Attribution 4.0 International License.
