ANTIBACTERIAL ACTIVITY TEST OF ETHANOL EXTRACT 70% OF FALOAK BARK (Sterculia quadrifida R.Br) ON Klebsiella Pneumoniae BACTERIA
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 70% KULIT BATANG FALOAK (Sterculia quadrifida R.Br) TERHADAP BAKTERI Klebsiella Pneumoniae
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Shita Anggenella Dupe(1*)
Universitas Nusa Cendana
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Rr. Listyawati Nurina(2)
Nusa Cendana University
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Efrisca M. Br Damanik(3)
Nusa Cendana University
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Prisca Deviani Pakan(4)
Nusa Cendana University
(*) Corresponding Author
Abstract
Introduction: Pneumonia is a common lower respiratory infection affecting all ages, caused by bacteria, viruses, fungi, or parasites. Klebsiella pneumoniae is a bacterial cause showing high antibiotic resistance, complicating treatment. As a result, alternative treatments using medicinal plants with antibacterial properties are needed. One promising plant is faloak (Sterculia quadrifida R.Br), traditionally used in herbal medicine and believed to have potential antibacterial effects worth further investigation.
Methods: This study employed a true experimental method with a post-test only control group design. The treatment groups were given 70% ethanol extract of faloak bark at various concentrations (100%, 50%, 25%, 12.5%, 6.25%, and 3.12%). There were also a positive control group (meropenem antibiotic) and a negative control group (sterile distilled water). Data were analyzed using the Kruskal-Wallis test.
Results: The 70% ethanol extract of faloak bark showed antibacterial activity against Klebsiella pneumoniae, with a significance value of p = 0.002 (< 0.05), indicating a significant difference in the inhibition zone diameters.
Discussion: The extract demonstrated antibacterial properties and the ability to inhibit the growth of Klebsiella pneumoniae.
Conclusion: The 70% ethanol extract of faloak bark (Sterculia quadrifida R.Br) exhibits antibacterial activity against Klebsiella pneumoniae.
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