In Vitro Antibacterial Activity Test of Ethanolic Extract of Kersen (Muntingia calabura L.) Leaves Against the Growth of Escherichia coli
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Abigail Eugelia Veterine Angsar(1*)
Universitas Nusa Cendana
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Rr Listyawati Nurina(2)
Universitas Nusa Cendana
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Gottfrieda Patiencia Taeng-Ob Adang(3)
Universitas Nusa Cendana
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Arley Sadra Telussa(4)
Universitas Nusa Cendana
(*) Corresponding Author
Abstract
Background: Diarrhea is a global health problem that causes millions of deaths every year. Treating diarrhea often involves the use of antibiotics, but antibiotic resistance is a serious problem. Cherry plants (Muntingia calabura L.) has been used traditionally to treatt infections . This research can provide new insights regarding the potential of using cherry plants as an alternative for treating bacterial infections without relying only on antibiotics.
Objective: To determine the antibacterial activity of ethanol extracts from the cherry leaves (Muntingia calabura L.) against the Escherichia coli growth.
Methods: This research is using a true experimental method with a post-test only control group design. The bacteria used is Escherichia coli with 8 treatment groups, the positive control group using ciprofloxacin, the negative control group using sterile aquadest, and six concentrations of cherry leaf extract treatment groups. The data was analyse with One Way Anova test.
Results and Discussion: Inhibition zones produced at the concentrations of 100%, 50%, 25%, 12.5%, 6.25%, 3.125% measuring 15.39 mm ; 14.02 mm; 11.82 mm; 10.82 mm; 9.64 mm; 8.32 mm , indicating strong to moderate antibacterial effects.
Conclusion: Ethanol extracts of cherry leaves (Muntingia calabura L.) exhibit antibacterial activity against Escherichia coli in vitro.
Keywords: Ethanol Extracts from Cherry Leaves, Antibacterial Activity, Escherichia coli, in vitro.
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References
2. The top 10 causes of death. World Health Organization. 2020. Tersedia pada: https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death
3. Kementerian Kesehatan Republik Indonesia. Profil Kesehatan Indonesia 2021. Pusdatin Kemenkes Indonesia. 2022.
4. Jumlah Kasus Penyakit Menurut Kabupaten/Kota dan Jenis Penyakit. Badan Pusat Statistik Provinsi Nusa Tenggara Timur. 2022.
5. Widoyono. Penyakit Tropis: Epidemiologi, Penularan, Pencegahan dan Pemberantasannya. Jakarta: Penerbit Erlangga; 2011.
6. Kementerian Kesehatan Republik Indonesia. Pedoman Pencegahan dan Pengendalian Infeksi di Fasilitas Pelayanan Kesehatan. Vol. 87. 2017.
7. Kementerian Kesehatan Republik Indonesia. Pedoman Penggunaan Antibiotik. 2021.
8. Nurjanah GS, Cahyadi AI, Windria S. Escherichia Coli Resistance To Various Kinds of Antibiotics in Animals and Humans: a Literature Study. Indonesia Medicus Veterinus. 2020;9(6):970–83.
9. Kementerian Kesehatan Republik Indonesia. Perkembangan Obat dan Pengobatan Tradisional Dalam Kesehatan Masyarakat dan Pemanfaatannya di Rumah Sakit. 2022.
10. Ansori ANM, Kharisma VD, Solikhah TI. Medicinal properties of Muntingia calabura L.: A Review. Research Journal of Pharmacy and Technology. 2021;14(8):4509–12.
11. Zahroh R, Musriana. Pemberian Rebusan Daun Kersen Menurunkan Kadar Glukosa Darah Pasien Diabetes Mellitus Tipe 2. Journals of Ners Community. 2018;07(2):102–8.
12. Handoko DA, Setyawati T, Asrinawati AN. Uji Efektivitas Antibakteri Ekstrak Daun Kersen (Muntigia calabura L.) terhadap Bakteri Escherichia coli. Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan. 2019;6(1):9–21.
13. Gurning K, Simanjuntak HA, Purba H, Situmorang RFR, Barus L, Silaban S. Determination of Total Tannins and Antibacterial Activities Ethanol Extraction Seri (Muntingia calabura L.) Leaves. Journal of Physics: Conference Series. 2021.
14. Azizah F, Listiana L, Juniawan M, Sholihah Y. Uji Antibakteri Perasan Daun Kersen (Muntingia Calabura L) Dalam Berbagai. Jurnal Pedago Biologi. 2022;10(1):285–93.
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