SIMULASI INTERAKTIF SCAFFOLD CHT-HA-LA-MDo BERBASIS MATLAB BERDASARKAN DATA EKSPERIMEN

MATLAB-Based Interactive Simulation of Chitosan–HA–MDo Scaffold Validated by Experimental Data

  • Mira Setiana(1*)
    Program Studi Teknik Biomedis, Fakultas Sains dan Teknologi, Universitas PGRI Yogyakarta
  • Bangkit Ina Ferawati(2)
    Program Studi Teknik Biomedis, Fakultas Sains dan Teknologi, Universitas PGRI Yogyakarta
    • (*) Corresponding Author
DOI: https://doi.org/10.35508/fisa.v11i1.25584
Keywords: Scaffold biopolimer, analisis ukuran pori, simulasi interaktif, MATLAB App Designer

Abstract

Scaffold berbasis biopolimer banyak digunakan dalam rekayasa jaringan karena kemampuannya dalam mendukung pertumbuhan sel serta memiliki sifat biodegradabel dan biokompatibel. Salah satu kombinasi material yang menjanjikan adalah Chitosan dan Hyaluronic Acid (HA), dengan penambahan Oxidized Maltodextrin (MDo) untuk meningkatkan kestabilan dan kekuatan mekanik scaffold. Dalam formulasi ini, Lactic Acid (LA) juga digunakan sebagai komponen pelarut dengan konsentrasi tetap sebesar 1% untuk membantu proses protonasi chitosan dan menjaga homogenitas larutan. Penelitian ini mengembangkan simulasi interaktif berbasis MATLAB App Designer untuk memvisualisasikan dan menganalisis struktur pori scaffold secara digital. Simulasi mengintegrasikan parameter konsentrasi HA dan MDo serta menghasilkan visualisasi tiga dimensi struktur pori dan histogram distribusi ukuran pori. Nilai rata-rata ukuran pori yang dihasilkan menunjukkan kesesuaian dengan hasil pengamatan eksperimental yang telah dilaporkan pada penelitian terdahulu. Fitur tambahan seperti ekspor ke Excel dan PDF disediakan untuk mendukung dokumentasi hasil secara otomatis. Aplikasi ini diharapkan dapat berfungsi sebagai alat bantu edukatif sekaligus fondasi awal untuk pengembangan sistem prediktif berbasis data dalam desain scaffold biomaterial.

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Published
2026-04-27
How to Cite
Setiana, M., & Ferawati, B. (2026). SIMULASI INTERAKTIF SCAFFOLD CHT-HA-LA-MDo BERBASIS MATLAB BERDASARKAN DATA EKSPERIMEN. Jurnal Fisika : Fisika Sains Dan Aplikasinya, 11(1), 65-71. https://doi.org/10.35508/fisa.v11i1.25584
Issue
Vol 11 No 1 (2026): Jurnal Fisika : Fisika Sains dan Aplikasinya
Section
Articles

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Jl. Adisucipto, Penfui-Kupang, Lasiana, Klp. Lima, Kota Kupang, Nusa Tenggara Timur., Indonesia

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